Gene name:
Lpcat2 (Aytl1;Aytl1a;Lpcat2a) ;
Protein name:
Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2;LPCAT-2;LysoPC acyltransferase 2) ;
Alternative:
1-alkylglycerophosphocholine O-acetyltransferase ;2.3.1.51;1-acylglycerophosphocholine O-acyltransferase (1-AGP acyltransferase 11) ;Acyltransferase-like 1 (Acetyl-CoA:lyso-PAF acetyltransferase) ;2.3.1.67;Acetyl-CoA:lyso-platelet-activating factor acetyltransferase (Acetyl-CoA:lyso-PAF acetyltransferase;Lyso-PAF acetyltransferase;LysoPAFAT) ;Acyltransferase-like 1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-alkyl-phosphatidylcholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases.
Subcellular Location:
Endoplasmic reticulum membrane
Single-pass type II membrane protein
Golgi apparatus membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MNRCAEAAAV | AATVPGSGVG | DSGLRPPMVP | RQASFFPPPV | PNPFVQQTRI |
100:
SAARRLQMIL | LGIILLPVRA | LLVGLVLLLA | WPFAVISTVC | CPKKLTHPIS |
150:
DWRRKITQPA | LKFLGRAMFF | SMGFRVTVKG | KVASPLEAPI | FVVAPHSTFF |
200:
DGIACVVAGL | PSLVSRNENA | QTPLVGRLLR | ALQPVLVSRV | DPDSRKNTIN |
250:
EIKKRAMSGG | EWPQILVFPE | GTCTNRSCLI | TFKPGAFIPG | VPVQPVLLRY |
300:
PNKLDTVTWT | WQGYTFIQLC | VLTFCQLFTK | VEVEFMPVQA | PSEEERNDPV |
350:
LFASRVRNLM | AEALEIPVTD | HTYEDCRLMI | SAGQLTLPME | AGLVEFTKIS |
400:
RKLKLDWDGI | RKHLDEYASI | ASSAKGGRIG | ASSAKGGRIG | PVSDVLRQLF |
450:
ALFDRNNDGS | IDFREYVIGL | AVLCNPANTE | DIIQVAFKLF | DVDEDGYITE |
500:
EEFCTILQAS | LGVPDLNVSG | LFREIAQGDS | VSYEEFKSFA | LKHPEYAKIF |
544:
TTYLDLQTCH | VFSLPEDVQT | APSVASNKVS | PESHEEGTSG | KKVD
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat LPC acyltransferase 2
ELISA Kit for Rat LPC acyltransferase 2
ELISA Kit for Rat LPC acyltransferase 2
CLIA Kit for Rat LPC acyltransferase 2
CLIA Kit for Rat LPC acyltransferase 2
CLIA Kit for Rat LPC acyltransferase 2
Polyclonal Antibody for Rat LPC acyltransferase 2
Polyclonal Antibody for Rat LPC acyltransferase 2
Polyclonal Antibody for Rat LPC acyltransferase 2
Monoclonal Antibody for Rat LPC acyltransferase 2
Monoclonal Antibody for Rat LPC acyltransferase 2
Monoclonal Antibody for Rat LPC acyltransferase 2
Protein for Rat LPC acyltransferase 2
Protein for Rat LPC acyltransferase 2
Protein for Rat LPC acyltransferase 2
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Gibbs R.A.
,
Weinstock G.M.
,
Metzker M.L.
,
Muzny D.M.
,
Sodergren E.J.
,
Scherer S.
,
Scott G.
,
Steffen D.
,
Worley K.C.
,
Burch P.E.
,
Okwuonu G.
,
Hines S.
,
Lewis L.
,
Deramo C.
,
Delgado O.
,
Dugan-Rocha S.
,
Miner G.
,
Morgan M.
,
Hawes A.
,
Gill R.
,
Holt R.A.
,
Adams M.D.
,
Amanatides P.G.
,
Baden-Tillson H.
,
Barnstead M.
,
Chin S.
,
Evans C.A.
,
Ferriera S.
,
Fosler C.
,
Glodek A.
,
Gu Z.
,
Jennings D.
,
Kraft C.L.
,
Nguyen T.
,
Pfannkoch C.M.
,
Sitter C.
,
Sutton G.G.
,
Venter J.C.
,
Woodage T.
,
Smith D.
,
Lee H.-M.
,
Gustafson E.
,
Cahill P.
,
Kana A.
,
Doucette-Stamm L.
,
Weinstock K.
,
Fechtel K.
,
Weiss R.B.
,
Dunn D.M.
,
Green E.D.
,
Blakesley R.W.
,
Bouffard G.G.
,
De Jong P.J.
,
Osoegawa K.
,
Zhu B.
,
Marra M.
,
Schein J.
,
Bosdet I.
,
Fjell C.
,
Jones S.
,
Krzywinski M.
,
Mathewson C.
,
Siddiqui A.
,
Wye N.
,
McPherson J.
,
Zhao S.
,
Fraser C.M.
,
Shetty J.
,
Shatsman S.
,
Geer K.
,
Chen Y.
,
Abramzon S.
,
Nierman W.C.
,
Havlak P.H.
,
Chen R.
,
Durbin K.J.
,
Egan A.
,
Ren Y.
,
Song X.-Z.
,
Li B.
,
Liu Y.
,
Qin X.
,
Cawley S.
,
Cooney A.J.
,
D'Souza L.M.
,
Martin K.
,
Wu J.Q.
,
Gonzalez-Garay M.L.
,
Jackson A.R.
,
Kalafus K.J.
,
McLeod M.P.
,
Milosavljevic A.
,
Virk D.
,
Volkov A.
,
Wheeler D.A.
,
Zhang Z.
,
Bailey J.A.
,
Eichler E.E.
,
Tuzun E.
,
Birney E.
,
Mongin E.
,
Ureta-Vidal A.
,
Woodwark C.
,
Zdobnov E.
,
Bork P.
,
Suyama M.
,
Torrents D.
,
Alexandersson M.
,
Trask B.J.
,
Young J.M.
,
Huang H.
,
Wang H.
,
Xing H.
,
Daniels S.
,
Gietzen D.
,
Schmidt J.
,
Stevens K.
,
Vitt U.
,
Wingrove J.
,
Camara F.
,
Mar Alba M.
,
Abril J.F.
,
Guigo R.
,
Smit A.
,
Dubchak I.
,
Rubin E.M.
,
Couronne O.
,
Poliakov A.
,
Huebner N.
,
Ganten D.
,
Goesele C.
,
Hummel O.
,
Kreitler T.
,
Lee Y.-A.
,
Monti J.
,
Schulz H.
,
Zimdahl H.
,
Himmelbauer H.
,
Lehrach H.
,
Jacob H.J.
,
Bromberg S.
,
Gullings-Handley J.
,
Jensen-Seaman M.I.
,
Kwitek A.E.
,
Lazar J.
,
Pasko D.
,
Tonellato P.J.
,
Twigger S.
,
Ponting C.P.
,
Duarte J.M.
,
Rice S.
,
Goodstadt L.
,
Beatson S.A.
,
Emes R.D.
,
Winter E.E.
,
Webber C.
,
Brandt P.
,
Nyakatura G.
,
Adetobi M.
,
Chiaromonte F.
,
Elnitski L.
,
Eswara P.
,
Hardison R.C.
,
Hou M.
,
Kolbe D.
,
Makova K.
,
Miller W.
,
Nekrutenko A.
,
Riemer C.
,
Schwartz S.
,
Taylor J.
,
Yang S.
,
Zhang Y.
,
Lindpaintner K.
,
Andrews T.D.
,
Caccamo M.
,
Clamp M.
,
Clarke L.
,
Curwen V.
,
Durbin R.M.
,
Eyras E.
,
Searle S.M.
,
Cooper G.M.
,
Batzoglou S.
,
Brudno M.
,
Sidow A.
,
Stone E.A.
,
Payseur B.A.
,
Bourque G.
,
Lopez-Otin C.
,
Puente X.S.
,
Chakrabarti K.
,
Chatterji S.
,
Dewey C.
,
Pachter L.
,
Bray N.
,
Yap V.B.
,
Caspi A.
,
Tesler G.
,
Pevzner P.A.
,
Haussler D.
,
Roskin K.M.
,
Baertsch R.
,
Clawson H.
,
Furey T.S.
,
Hinrichs A.S.
,
Karolchik D.
,
Kent W.J.
,
Rosenbloom K.R.
,
Trumbower H.
,
Weirauch M.
,
Cooper D.N.
,
Stenson P.D.
,
Ma B.
,
Brent M.
,
Arumugam M.
,
Shteynberg D.
,
Copley R.R.
,
Taylor M.S.
,
Riethman H.
,
Mudunuri U.
,
Peterson J.
,
Guyer M.
,
Felsenfeld A.
,
Old S.
,
Mockrin S.
,
Collins F.S.
more...
Nature428:493-521(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Brown Norway .